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Selective tubular activation of hypoxia-inducible factor-2α has dual effects on renal fibrosis

Hypoxia-inducible factor (HIF) is a key transcriptional factor in the response to hypoxia. Although the effect of HIF activation in chronic kidney disease (CKD) has been widely evaluated, the results have been inconsistent until now. This study aimed to investigate the effects of HIF-2α activation o...

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Detalles Bibliográficos
Autores principales: Kong, Kyoung Hye, Oh, Hyung Jung, Lim, Beom Jin, Kim, Minsuk, Han, Ki-Hwan, Choi, Youn-Hee, Kwon, Kihwan, Nam, Bo Young, Park, Kyoung Sook, Park, Jung Tak, Han, Seung Hyeok, Yoo, Tae-Hyun, Lee, Shina, Kim, Seung-Jung, Kang, Duk-Hee, Choi, Kyu Bok, Eremina, Vera, Quaggin, Susan E., Ryu, Dong-Ryeol, Kang, Shin-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596020/
https://www.ncbi.nlm.nih.gov/pubmed/28900259
http://dx.doi.org/10.1038/s41598-017-11829-2