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Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

Immunological events in acute HIV-1 infection before peak viremia (hyperacute phase) may contribute to the development of broadly cross-neutralizing antibodies. Here, we used pre-infection and acute-infection peripheral blood mononuclear cells and plasma samples from 22 women, including 10 who initi...

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Detalles Bibliográficos
Autores principales: Mabuka, Jenniffer M., Dugast, Anne-Sophie, Muema, Daniel M., Reddy, Tarylee, Ramlakhan, Yathisha, Euler, Zelda, Ismail, Nasreen, Moodley, Amber, Dong, Krista L., Morris, Lynn, Walker, Bruce D., Alter, Galit, Ndung’u, Thumbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596076/
https://www.ncbi.nlm.nih.gov/pubmed/28943879
http://dx.doi.org/10.3389/fimmu.2017.01104