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Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways
MYC activation at modest levels has been frequently found in hepatocellular carcinoma. However, its significance in hepatocarcinogenesis has remained obscure. Here we examined the role of Myc activation in mouse liver tumours induced by hepatocytic expression of myristoylated AKT (AKT) and/or mutant...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596209/ https://www.ncbi.nlm.nih.gov/pubmed/28481866 http://dx.doi.org/10.1038/onc.2017.114 |