Cargando…
Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes
Lipoic acid is an essential metabolic cofactor added as a posttranslational modification on several multimeric enzyme complexes. These protein complexes, evolutionarily conserved from bacteria to humans, are core regulators of cellular metabolism. While the multistep enzymatic process of adding lipo...
Autores principales: | Rowland, Elizabeth A., Greco, Todd M., Snowden, Caroline K., McCabe, Anne L., Silhavy, Thomas J., Cristea, Ileana M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596343/ https://www.ncbi.nlm.nih.gov/pubmed/28900027 http://dx.doi.org/10.1128/mBio.01096-17 |
Ejemplares similares
-
Sirtuins Are Evolutionarily Conserved Viral Restriction Factors
por: Koyuncu, Emre, et al.
Publicado: (2014) -
The Amidase Domain of Lipoamidase Specifically Inactivates Lipoylated Proteins In Vivo
por: Spalding, Maroya D., et al.
Publicado: (2009) -
Using Lipoamidase as a Novel Probe To Interrogate the Importance of Lipoylation in Plasmodium falciparum
por: Jhun, Hugo, et al.
Publicado: (2018) -
The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection
por: Sheng, Xinlei, et al.
Publicado: (2021) -
Sirtuins are Not Conserved Longevity Genes
por: Brenner, Charles
Publicado: (2022)