Combined genotypes of the MBL2 gene related to low mannose-binding lectin levels are associated with vaso-occlusive events in children with sickle cell anemia

Sickle cell anemia (SCA) presents heterogenous clinical manifestations that cannot be explained solely by alterations to hemoglobin (Hb); other components such as endothelial adhesion, thrombosis and inflammation may be involved. The mannose-binding lectin (MBL) has an important role in innate immun...

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Detalles Bibliográficos
Autores principales: Medeiros, Fernanda Silva, de Mendonça, Taciana Furtado, Lopes, Katiuscia Araújo de Miranda, França, Laís Medeiros da Câmara, da Silva, Andreia Soares, Vasconcelos, Luydson Richardson Silva, de Oliveira, Maria do Carmo Valgueiro Costa, dos Anjos, Ana Cláudia Mendonça, Hatzlhofer, Betânia Lucena Domingues, Bezerra, Marcos André Cavalcanti, Araújo, Aderson da Silva, Moura, Patrícia, Cavalcanti, Maria do Socorro de Mendonça
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2017
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596363/
https://www.ncbi.nlm.nih.gov/pubmed/28837214
http://dx.doi.org/10.1590/1678-4685-GMB-2016-0161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596363/
https://www.ncbi.nlm.nih.gov/pubmed/28837214
http://dx.doi.org/10.1590/1678-4685-GMB-2016-0161

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