Cargando…

In vivo chemotherapeutic insight of a novel isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation

Chemotherapy is one of the major approaches for the treatment of cancer. Therefore, the development of new chemotherapy drugs is an important aspect of medicinal chemistry. Chemotherapeutic agents include isocoumarins, which are privileged structures with potential antitumoral activity. Herein, a ne...

Descripción completa

Detalles Bibliográficos
Autores principales: de Araújo, Flávio Henrique Souza, de Figueiredo, Débora Rojas, Auharek, Sarah Alves, Pesarini, João Renato, Meza, Alisson, Gomes, Roberto da Silva, Monreal, Antônio Carlos Duenhas, Antoniolli-Silva, Andréia Conceição Milan Brochado, de Lima, Dênis Pires, Kassuya, Candida Aparecida Leite, Beatriz, Adilson, Oliveira, Rodrigo Juliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596378/
https://www.ncbi.nlm.nih.gov/pubmed/28898353
http://dx.doi.org/10.1590/1678-4685-GMB-2016-0316