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From Waldenström’s macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation

Transformation of Waldenström’s macroglobulinemia (WM) to diffuse large B-cell lymphoma (DLBCL) occurs in up to 10% of patients and is associated with an adverse outcome. Here we performed the first whole-exome sequencing study of WM patients who evolved to DLBCL and report the genetic alterations t...

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Detalles Bibliográficos
Autores principales: Jiménez, C, Alonso-Álvarez, S, Alcoceba, M, Ordóñez, G R, García-Álvarez, M, Prieto-Conde, M I, Chillón, M C, Balanzategui, A, Corral, R, Marín, L A, Gutiérrez, N C, Puig, N, Sarasquete, M E, González, M, García-Sanz, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596383/
https://www.ncbi.nlm.nih.gov/pubmed/28841204
http://dx.doi.org/10.1038/bcj.2017.72