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Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish

The SOX4 transcription factor is a key regulator of embryonic development, cell-fate decision, cellular differentiation and oncogenesis. Abnormal expression of SOX4 is related to malignant tumor transformation and cancer metastasis. However, no reports are available regarding the clinical significan...

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Detalles Bibliográficos
Autores principales: Lu, J-W, Hsieh, M-S, Hou, H-A, Chen, C-Y, Tien, H-F, Lin, L-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596385/
https://www.ncbi.nlm.nih.gov/pubmed/28841206
http://dx.doi.org/10.1038/bcj.2017.74