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RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation

Loss of epithelial differentiation and extracellular matrix (ECM) remodeling are known to facilitate cancer progression and are associated with poor prognosis in patients with lung cancer. We have identified Receptor-interacting serine/threonine protein kinase 4 (RIP4) as a regulator of tumor differ...

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Detalles Bibliográficos
Autores principales: Kopparam, Jawahar, Chiffelle, Johanna, Angelino, Paolo, Piersigilli, Alessandra, Zangger, Nadine, Delorenzi, Mauro, Meylan, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596425/
https://www.ncbi.nlm.nih.gov/pubmed/28574510
http://dx.doi.org/10.1038/cdd.2017.81