p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress

Physiological and pathological conditions that affect the folding capacity of the endoplasmic reticulum (ER) provoke ER stress and trigger the unfolded protein response (UPR). The UPR aims to either restore the balance between newly synthesized and misfolded proteins or if the damage is severe, to t...

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Detalles Bibliográficos
Autores principales: López, Ignacio, Tournillon, Anne-Sophie, Prado Martins, Rodrigo, Karakostis, Konstantinos, Malbert-Colas, Laurence, Nylander, Karin, Fåhraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596431/
https://www.ncbi.nlm.nih.gov/pubmed/28622297
http://dx.doi.org/10.1038/cdd.2017.96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596431/
https://www.ncbi.nlm.nih.gov/pubmed/28622297
http://dx.doi.org/10.1038/cdd.2017.96

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