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Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging

Rationale: Ultrasound-mediated opening of the Blood-Brain Barrier(BBB) has shown exciting potential for the treatment of Alzheimer's disease(AD). Studies in transgenic mouse models have shown that this approach can reduce plaque pathology and improve spatial memory. Before clinical translation...

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Detalles Bibliográficos
Autores principales: O'Reilly, Meaghan Anne, Jones, Ryan Matthew, Barrett, Edward, Schwab, Anthony, Head, Elizabeth, Hynynen, Kullervo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596444/
https://www.ncbi.nlm.nih.gov/pubmed/28912896
http://dx.doi.org/10.7150/thno.20621