Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y(12) and P2Y(13) receptors in neuropathic pain rats

BACKGROUND: More evidence suggests that dorsal spinal cord microglia is an important site contributing to CB2 receptor-mediated analgesia. The upregulation of P2Y(12) and P2Y(13) purinoceptors in spinal dorsal horn microglia is involved in the development of pain behavior caused by peripheral nerve...

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Detalles Bibliográficos
Autores principales: Niu, Juan, Huang, Dujuan, Zhou, Rui, Yue, MingXia, Xu, Tao, Yang, Junna, He, Li, Tian, Hong, Liu, XiaoHong, Zeng, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596460/
https://www.ncbi.nlm.nih.gov/pubmed/28899427
http://dx.doi.org/10.1186/s12974-017-0960-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596460/
https://www.ncbi.nlm.nih.gov/pubmed/28899427
http://dx.doi.org/10.1186/s12974-017-0960-0

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