Cargando…

Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y(12) and P2Y(13) receptors in neuropathic pain rats

BACKGROUND: More evidence suggests that dorsal spinal cord microglia is an important site contributing to CB2 receptor-mediated analgesia. The upregulation of P2Y(12) and P2Y(13) purinoceptors in spinal dorsal horn microglia is involved in the development of pain behavior caused by peripheral nerve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niu, Juan, Huang, Dujuan, Zhou, Rui, Yue, MingXia, Xu, Tao, Yang, Junna, He, Li, Tian, Hong, Liu, XiaoHong, Zeng, Junwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596460/ https://www.ncbi.nlm.nih.gov/pubmed/28899427 http://dx.doi.org/10.1186/s12974-017-0960-0

Ejemplares similares

Activation of spinal dorsal horn P2Y(13) receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain
por: Zhou, Rui, et al.
Publicado: (2018)

Protective role of neuronal and lymphoid cannabinoid CB(2) receptors in neuropathic pain
por: Cabañero, David, et al.
Publicado: (2020)

Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn
por: Zheng, Xiao-bo, et al.
Publicado: (2019)

Cannabinoid CB(1) and CB(2) Receptor Signaling and Bias
por: Ibsen, Mikkel Søes, et al.
Publicado: (2017)

Evidence for a novel functional role of cannabinoid CB(2) receptors in the thalamus of neuropathic rats
por: Jhaveri, M D, et al.
Publicado: (2008)

Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018)

Antiallodynic Effects of Cannabinoid Receptor 2 (CB(2)R) Agonists on Retrovirus Infection-Induced Neuropathic Pain
por: Sheng, Wen S., et al.
Publicado: (2019)

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn
por: Nelson, Tyler S., et al.
Publicado: (2019)

Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB(2) receptor
por: Patel, Monica, et al.
Publicado: (2023)

P2Y(12) and P2Y(13) receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia
por: Liu, Pei-Wen, et al.
Publicado: (2017)

Cannabinoid Receptor CB(2) Modulates Axon Guidance
por: Duff, Gabriel, et al.
Publicado: (2013)

Editorial: Therapeutic potential of the cannabinoid CB2 receptor
por: Smoum, Reem, et al.
Publicado: (2022)

Microglial Cannabinoid CB(2) Receptors in Pain Modulation
por: Xu, Kangtai, et al.
Publicado: (2023)

Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain
por: Zhang, Zhi-Jun, et al.
Publicado: (2012)

Brain Cannabinoid CB(2) Receptors Modulate Cocaine’s Actions in Mice
por: Xi, Zheng-Xiong, et al.
Publicado: (2011)

Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Involving the P2Y12 Receptor in the Dorsal Root Ganglia
por: Jia, Tianyu, et al.
Publicado: (2018)

Cannabinoid Receptors CB1 and CB2 Modulate the Electroretinographic Waves in Vervet Monkeys
por: Bouskila, Joseph, et al.
Publicado: (2016)

Stimulation of cannabinoid receptor 2 (CB(2)) suppresses microglial activation
por: Ehrhart, Jared, et al.
Publicado: (2005)

Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain
por: Ghosh, Krishna, et al.
Publicado: (2022)

Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS
por: Onaivi, E.S
Publicado: (2011)

Chain Substituted Cannabilactones with Selectivity for the CB2 Cannabinoid Receptor
por: Alapafuja, Shakiru O., et al.
Publicado: (2019)

Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB(2) Receptor
por: Morales, Paula, et al.
Publicado: (2020)

Cholesterol as a modulator of cannabinoid receptor CB(2) signaling
por: Yeliseev, Alexei, et al.
Publicado: (2021)

Structural basis of selective cannabinoid CB(2) receptor activation
por: Li, Xiaoting, et al.
Publicado: (2023)

Expression and Function of Cannabinoid Receptors CB1 and CB2 and Their Cognate Cannabinoid Ligands in Murine Embryonic Stem Cells
por: Jiang, Shuxian, et al.
Publicado: (2007)

P2X receptor-mediated purinergic sensory pathways to the spinal cord dorsal horn
por: Gu, Jianguo G., et al.
Publicado: (2004)

Functional characterization of the novel cannabinoid receptor GPR55 and its modulation by CB(1 )and CB(2 )receptors
por: Balenga, Nariman, et al.
Publicado: (2008)

Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity
por: Franks, Lirit N., et al.
Publicado: (2016)

Singular Location and Signaling Profile of Adenosine A(2A)-Cannabinoid CB(1) Receptor Heteromers in the Dorsal Striatum
por: Moreno, Estefanía, et al.
Publicado: (2018)

Immunolocalization of cannabinoid receptor type 1 and CB2 cannabinoid receptors, and transient receptor potential vanilloid channels in pterygium
por: Assimakopoulou, Martha, et al.
Publicado: (2017)

P2X3 receptor expression in dorsal horn of spinal cord and pain threshold after estrogen therapy for prevention therapy in neuropathic pain
por: Rosyidi, Rohadi Muhammad, et al.
Publicado: (2020)

Effects of pro‐inflammatory cytokines on cannabinoid CB (1) and CB (2) receptors in immune cells
por: Jean‐Gilles, L., et al.
Publicado: (2015)

Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms
por: Soderstrom, Ken, et al.
Publicado: (2017)

Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons
por: Tong, Chi-Kun, et al.
Publicado: (2008)

Differential Activation of Intracellular versus Plasmalemmal CB(2) Cannabinoid Receptors
por: Brailoiu, G. Cristina, et al.
Publicado: (2014)

CB(2) Cannabinoid Receptor As Potential Target against Alzheimer's Disease
por: Aso, Ester, et al.
Publicado: (2016)

Cannabinoid CB(2) receptors in the mouse brain: relevance for Alzheimer’s disease
por: López, Alicia, et al.
Publicado: (2018)

Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors
por: Aby, Franck, et al.
Publicado: (2018)

Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor
por: Zhou, Yifan, et al.
Publicado: (2023)

An Update on Non-CB(1), Non-CB(2) Cannabinoid Related G-Protein-Coupled Receptors
por: Morales, Paula, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pot75khkulfr1oa1jn3d0p499q