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Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
BACKGROUND: Uncovering mechanisms of epigenome evolution is an essential step towards understanding the evolution of different cellular phenotypes. While studies have confirmed DNA methylation as a conserved epigenetic mechanism in mammalian development, little is known about the conservation of tis...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596466/ https://www.ncbi.nlm.nih.gov/pubmed/28899353 http://dx.doi.org/10.1186/s12864-017-4115-6 |