Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

BACKGROUND: Uncovering mechanisms of epigenome evolution is an essential step towards understanding the evolution of different cellular phenotypes. While studies have confirmed DNA methylation as a conserved epigenetic mechanism in mammalian development, little is known about the conservation of tis...

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Detalles Bibliográficos
Autores principales: Zhou, Jia, Sears, Renee L., Xing, Xiaoyun, Zhang, Bo, Li, Daofeng, Rockweiler, Nicole B., Jang, Hyo Sik, Choudhary, Mayank N.K., Lee, Hyung Joo, Lowdon, Rebecca F., Arand, Jason, Tabers, Brianne, Gu, C. Charles, Cicero, Theodore J., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596466/
https://www.ncbi.nlm.nih.gov/pubmed/28899353
http://dx.doi.org/10.1186/s12864-017-4115-6

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