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NOTCH1 Activation Depletes the Pool of Side Population Stem Cells in ATL

BACKGROUND: HTLV-I infection is associated with the development of adult T-cell leukemia (ATL), a malignancy characterized by a high rate of disease relapse and poor survival. Previous studies reported the existence of side population (SP) cells in HTLV-I Tax transgenic mouse models. These studies s...

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Detalles Bibliográficos
Autores principales: Bai, Xue Tao, Yeh, Chien-Hung, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596512/
https://www.ncbi.nlm.nih.gov/pubmed/28920078