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FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway

Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to organ fibrogenesis, and we have reported that the anti-EndMT effect of N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) is associated with restoring expression of diabetes-suppressed fibroblast growth factor receptor (FGFR),...

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Detalles Bibliográficos
Autores principales: Li, Jinpeng, Shi, Sen, Srivastava, Swayam Prakash, Kitada, Munehiro, Nagai, Takako, Nitta, Kyoko, Kohno, Miyuki, Kanasaki, Keizo, Koya, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596544/
https://www.ncbi.nlm.nih.gov/pubmed/28771231
http://dx.doi.org/10.1038/cddis.2017.353