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LncRNA OIP5-AS1 loss-induced microRNA-410 accumulation regulates cell proliferation and apoptosis by targeting KLF10 via activating PTEN/PI3K/AKT pathway in multiple myeloma

Numerous studies confirmed that aberrant miRNAs expression contributes to multiple myeloma (MM) development and progression. However, the roles of specific miRNAs in MM remain to be investigated. In present study, we demonstrated that miR-410 expression was increased in MM newly diagnosed and relaps...

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Detalles Bibliográficos
Autores principales: Yang, Nan, Chen, Jinqiu, Zhang, Hui, Wang, Xiaman, Yao, Huan, Peng, Yue, Zhang, Wanggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596549/
https://www.ncbi.nlm.nih.gov/pubmed/28796257
http://dx.doi.org/10.1038/cddis.2017.358