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TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A

Autophagy is a highly inducible system of intracellular degradation that occurs in lysosomes or vacuoles. Transmembrane 74 (TMEM74) has been shown to induce autophagy. However, the mechanism by which TMEM74 stimulates autophagy and the impacts of TMEM74-induced autophagy on tumor cell survival remai...

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Detalles Bibliográficos
Autores principales: Sun, Yizhe, Chen, Yingyu, Zhang, Jingyu, Cao, Lulu, He, Minwei, Liu, Xi, Zhao, Ning, Yin, Ang, Huang, He, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596558/
https://www.ncbi.nlm.nih.gov/pubmed/29048433
http://dx.doi.org/10.1038/cddis.2017.370