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Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia

Macrophages are essential for the inflammatory response after an ischemic insult and thereby influence tissue recovery. For the oxygen sensing prolyl-4-hydroxylase domain enzyme (PHD) 2 a clear impact on the macrophage-mediated arteriogenic response after hind-limb ischemia has been demonstrated pre...

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Detalles Bibliográficos
Autores principales: Beneke, Angelika, Guentsch, Annemarie, Hillemann, Annette, Zieseniss, Anke, Swain, Lija, Katschinski, Dörthe M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596563/
https://www.ncbi.nlm.nih.gov/pubmed/28796258
http://dx.doi.org/10.1038/cddis.2017.375