MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner

Chemoresistance contributes to cancer relapse and increased mortality in a variety of cancer types, raising a pressing need to better understand the underlying mechanism. MUC1 is abnormally overexpressed in numerous carcinomas and associated with poor prognosis. However, the functional significance...

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Detalles Bibliográficos
Autores principales: Jin, Wei, Liao, Xiaodong, Lv, Yaping, Pang, Zhi, Wang, Yuming, Li, Quanfu, Liao, Yahui, Ye, Qing, Chen, Guoqiang, Zhao, Kewen, Huang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596566/
https://www.ncbi.nlm.nih.gov/pubmed/28796259
http://dx.doi.org/10.1038/cddis.2017.378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596566/
https://www.ncbi.nlm.nih.gov/pubmed/28796259
http://dx.doi.org/10.1038/cddis.2017.378

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