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MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner
Chemoresistance contributes to cancer relapse and increased mortality in a variety of cancer types, raising a pressing need to better understand the underlying mechanism. MUC1 is abnormally overexpressed in numerous carcinomas and associated with poor prognosis. However, the functional significance...
Autores principales: | Jin, Wei, Liao, Xiaodong, Lv, Yaping, Pang, Zhi, Wang, Yuming, Li, Quanfu, Liao, Yahui, Ye, Qing, Chen, Guoqiang, Zhao, Kewen, Huang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596566/ https://www.ncbi.nlm.nih.gov/pubmed/28796259 http://dx.doi.org/10.1038/cddis.2017.378 |
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