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Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway

DACT2, one of the Dact gene family members, was shown to function as a tumor suppressor. However, its function in gliomas remains largely unknown. In this study, we investigated the role of DACT2, underlying molecular mechanisms and its clinical significance in glioma patients. Downexpression of DAC...

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Detalles Bibliográficos
Autores principales: Tan, Ying, Li, Qiu-Meng, Huang, Ning, Cheng, Si, Zhao, Guan-Jian, Chen, Hong, Chen, Song, Tang, Zhao-Hua, Zhang, Wen-Qian, Huang, Qin, Cheng, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596571/
https://www.ncbi.nlm.nih.gov/pubmed/28796248
http://dx.doi.org/10.1038/cddis.2017.385