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Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway
DACT2, one of the Dact gene family members, was shown to function as a tumor suppressor. However, its function in gliomas remains largely unknown. In this study, we investigated the role of DACT2, underlying molecular mechanisms and its clinical significance in glioma patients. Downexpression of DAC...
Autores principales: | Tan, Ying, Li, Qiu-Meng, Huang, Ning, Cheng, Si, Zhao, Guan-Jian, Chen, Hong, Chen, Song, Tang, Zhao-Hua, Zhang, Wen-Qian, Huang, Qin, Cheng, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596571/ https://www.ncbi.nlm.nih.gov/pubmed/28796248 http://dx.doi.org/10.1038/cddis.2017.385 |
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