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Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance
Current preclinical models in tumor biology are limited in their ability to recapitulate relevant (patho-) physiological processes, including autophagy. Three-dimensional (3D) growth cultures have frequently been proposed to overcome the lack of correlation between two-dimensional (2D) monolayer cel...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596581/ https://www.ncbi.nlm.nih.gov/pubmed/28837150 http://dx.doi.org/10.1038/cddis.2017.398 |