Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance

Current preclinical models in tumor biology are limited in their ability to recapitulate relevant (patho-) physiological processes, including autophagy. Three-dimensional (3D) growth cultures have frequently been proposed to overcome the lack of correlation between two-dimensional (2D) monolayer cel...

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Detalles Bibliográficos
Autores principales: Bingel, Corinna, Koeneke, Emily, Ridinger, Johannes, Bittmann, Annika, Sill, Martin, Peterziel, Heike, Wrobel, Jagoda K, Rettig, Inga, Milde, Till, Fernekorn, Uta, Weise, Frank, Schober, Andreas, Witt, Olaf, Oehme, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596581/
https://www.ncbi.nlm.nih.gov/pubmed/28837150
http://dx.doi.org/10.1038/cddis.2017.398

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