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Cardamonin induces ROS-mediated G2/M phase arrest and apoptosis through inhibition of NF-κB pathway in nasopharyngeal carcinoma

Cardamonin has been demonstrated to have an inhibitory effect in many cancers, but its underlying mechanism remains elusive. Here, we studied, for the first time, the mechanism of cardamonin-induced nasopharyngeal carcinoma cell death both in vitro and in vivo. In our study, we showed that cardamoni...

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Detalles Bibliográficos
Autores principales: Li, Yuting, Qin, You, Yang, Chensu, Zhang, Haibo, Li, Yong, Wu, Bian, Huang, Jing, Zhou, Xiaoshu, Huang, Bo, Yang, Kunyu, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596588/
https://www.ncbi.nlm.nih.gov/pubmed/29048425
http://dx.doi.org/10.1038/cddis.2017.407