Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells

Doxorubicin (DOXO) treatment is limited by its cardiotoxicity, since it causes cardiac-progenitor-cell depletion. Although the cardioprotective role of the stromal cell-derived factor-1/C-X-C chemokine receptor type 4 (SDF1/CXCR4) axis is well established, its involvement during DOXO-induced cardiot...

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Detalles Bibliográficos
Autores principales: Beji, Sara, Milano, Giuseppina, Scopece, Alessandro, Cicchillitti, Lucia, Cencioni, Chiara, Picozza, Mario, D'Alessandra, Yuri, Pizzolato, Sarah, Bertolotti, Matteo, Spaltro, Gabriella, Raucci, Angela, Piaggio, Giulia, Pompilio, Giulio, Capogrossi, Maurizio C, Avitabile, Daniele, Magenta, Alessandra, Gambini, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596590/
https://www.ncbi.nlm.nih.gov/pubmed/28837147
http://dx.doi.org/10.1038/cddis.2017.409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596590/
https://www.ncbi.nlm.nih.gov/pubmed/28837147
http://dx.doi.org/10.1038/cddis.2017.409

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