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Mycobacterium abscessus glycopeptidolipids inhibit macrophage apoptosis and bacterial spreading by targeting mitochondrial cyclophilin D

Mycobacterium abscessus (MAB) is a species of nontuberculous mycobacteria (NTM) and a major causative pathogen of pulmonary diseases especially in patients with cystic fibrosis. MAB infection is notoriously difficult to treat because of its intrinsic or inducible resistance to most antibiotics. The...

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Detalles Bibliográficos
Autores principales: Whang, Jake, Back, Yong Woo, Lee, Kang-In, Fujiwara, Nagatoshi, Paik, Seungwha, Choi, Chul Hee, Park, Jeong-Kyu, Kim, Hwa-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596598/
https://www.ncbi.nlm.nih.gov/pubmed/28837151
http://dx.doi.org/10.1038/cddis.2017.420