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Splatter: simulation of single-cell RNA sequencing data

As single-cell RNA sequencing (scRNA-seq) technologies have rapidly developed, so have analysis methods. Many methods have been tested, developed, and validated using simulated datasets. Unfortunately, current simulations are often poorly documented, their similarity to real data is not demonstrated...

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Detalles Bibliográficos
Autores principales: Zappia, Luke, Phipson, Belinda, Oshlack, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596896/
https://www.ncbi.nlm.nih.gov/pubmed/28899397
http://dx.doi.org/10.1186/s13059-017-1305-0