Design of pilot studies to inform the construction of composite outcome measures

INTRODUCTION: Composite scales have recently been proposed as outcome measures for clinical trials. For example, the Preclinical Alzheimer's Cognitive Composite (PACC) is the sum of z-score normed component measures assessing episodic memory, timed executive function, and global cognition. Alte...

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Detalles Bibliográficos
Autores principales: Edland, Steven D., Ard, M. Colin, Li, Weiwei, Jiang, Lingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Featured Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596916/
https://www.ncbi.nlm.nih.gov/pubmed/28920073
http://dx.doi.org/10.1016/j.trci.2016.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596916/
https://www.ncbi.nlm.nih.gov/pubmed/28920073
http://dx.doi.org/10.1016/j.trci.2016.12.004

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