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Accurate nanoscale flexibility measurement of DNA and DNA–protein complexes by atomic force microscopy in liquid

The elasticity of double-stranded DNA (dsDNA), as described by its persistence length, is critical for many biological processes, including genomic regulation. A persistence length value can be obtained using atomic force microscopy (AFM) imaging. However, most AFM studies have been done by depositi...

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Detalles Bibliográficos
Autores principales: Murugesapillai, Divakaran, Bouaziz, Serge, Maher, L. James, Israeloff, Nathan E., Cameron, Craig E., Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597049/
https://www.ncbi.nlm.nih.gov/pubmed/28762410
http://dx.doi.org/10.1039/c7nr04231k