Multiscale biphasic modelling of peritumoural collagen microstructure: The effect of tumour growth on permeability and fluid flow

We present an in-silico model of avascular poroelastic tumour growth coupled with a multiscale biphasic description of the tumour–host environment. The model is specified to in-vitro data, facilitating biophysically realistic simulations of tumour spheroid growth into a dense collagen hydrogel. We u...

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Detalles Bibliográficos
Autores principales: Wijeratne, Peter A., Hipwell, John H., Hawkes, David J., Stylianopoulos, Triantafyllos, Vavourakis, Vasileios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597211/
https://www.ncbi.nlm.nih.gov/pubmed/28902902
http://dx.doi.org/10.1371/journal.pone.0184511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597211/
https://www.ncbi.nlm.nih.gov/pubmed/28902902
http://dx.doi.org/10.1371/journal.pone.0184511

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