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Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development

The tree-like structure of the mammalian lung is generated from branching morphogenesis, a reiterative process that is precisely regulated by numerous factors. How the cell surface and extra cellular matrix (ECM) molecules regulate this process is still poorly understood. Herein, we show that epithe...

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Detalles Bibliográficos
Autores principales: He, Hua, Huang, Meina, Sun, Shenfei, Wu, Yihui, Lin, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597256/
https://www.ncbi.nlm.nih.gov/pubmed/28859094
http://dx.doi.org/10.1371/journal.pgen.1006992