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P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria

A complete understanding of the mechanisms underlying the acquisition of protective immunity is crucial to improve vaccine strategies to eradicate malaria. However, it is still unclear whether recognition of damage signals influences the immune response to Plasmodium infection. Adenosine triphosphat...

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Detalles Bibliográficos
Autores principales: de Salles, Érika Machado, de Menezes, Maria Nogueira, Siqueira, Renan, Borges da Silva, Henrique, Amaral, Eduardo Pinheiro, Castillo-Méndez, Sheyla Inés, Cunha, Isabela, Cassado, Alexandra dos Anjos, Vieira, Flávia Sarmento, Olivieri, David Nicholas, Tadokoro, Carlos Eduardo, Alvarez, José Maria, Coutinho-Silva, Robson, D’Império-Lima, Maria Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597262/
https://www.ncbi.nlm.nih.gov/pubmed/28859168
http://dx.doi.org/10.1371/journal.ppat.1006595