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Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells
The short F-actins in the red blood cell (RBC) membrane skeleton are coated along their lengths by an equimolar combination of two tropomyosin isoforms, Tpm1.9 and Tpm3.1. We hypothesized that tropomyosin’s ability to stabilize F-actin regulates RBC morphology and mechanical properties. To test this...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597325/ https://www.ncbi.nlm.nih.gov/pubmed/28720661 http://dx.doi.org/10.1091/mbc.E16-10-0699 |