Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions

Transmembrane domains (TMDs) engage in protein-protein interactions that regulate many cellular processes, but the rules governing the specificity of these interactions are poorly understood. To discover these principles, we analyzed 26-residue model transmembrane proteins consisting exclusively of...

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Detalles Bibliográficos
Autores principales: He, Li, Steinocher, Helena, Shelar, Ashish, Cohen, Emily B, Heim, Erin N, Kragelund, Birthe B, Grigoryan, Gevorg, DiMaio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597333/
https://www.ncbi.nlm.nih.gov/pubmed/28869036
http://dx.doi.org/10.7554/eLife.27701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597333/
https://www.ncbi.nlm.nih.gov/pubmed/28869036
http://dx.doi.org/10.7554/eLife.27701

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