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Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions
Transmembrane domains (TMDs) engage in protein-protein interactions that regulate many cellular processes, but the rules governing the specificity of these interactions are poorly understood. To discover these principles, we analyzed 26-residue model transmembrane proteins consisting exclusively of...
Autores principales: | He, Li, Steinocher, Helena, Shelar, Ashish, Cohen, Emily B, Heim, Erin N, Kragelund, Birthe B, Grigoryan, Gevorg, DiMaio, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597333/ https://www.ncbi.nlm.nih.gov/pubmed/28869036 http://dx.doi.org/10.7554/eLife.27701 |
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