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Modulation of occluding junctions alters the hematopoietic niche to trigger immune activation

Stem cells are regulated by signals from their microenvironment, or niche. During Drosophila hematopoiesis, a niche regulates prohemocytes to control hemocyte production. Immune challenges activate cell-signalling to initiate the cellular and innate immune response. Specifically, certain immune chal...

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Detalles Bibliográficos
Autores principales: Khadilkar, Rohan J, Vogl, Wayne, Goodwin, Katharine, Tanentzapf, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597334/
https://www.ncbi.nlm.nih.gov/pubmed/28841136
http://dx.doi.org/10.7554/eLife.28081