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High yield reproducible rat model recapitulating human Barrett’s carcinogenesis

AIM: To efficiently replicate the biology and pathogenesis of human esophageal adenocarcinoma (EAC) using the modified Levrat model of end-to-side esophagojejunostomy. METHODS: End-to-side esophagojejunostomy was performed on rats to induce gastroduodenoesophageal reflux to develop EAC. Animals were...

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Detalles Bibliográficos
Autores principales: Matsui, Daisuke, Omstead, Ashten N, Kosovec, Juliann E, Komatsu, Yoshihiro, Lloyd, Emily J, Raphael, Hailey, Kelly, Ronan J, Zaidi, Ali H, Jobe, Blair A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597499/
https://www.ncbi.nlm.nih.gov/pubmed/28970723
http://dx.doi.org/10.3748/wjg.v23.i33.6077