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Anti-inflammatory Effect of Glucagon Like Peptide-1 Receptor Agonist, Exendin-4, through Modulation of IB1/JIP1 Expression and JNK Signaling in Stroke

Glucagon like peptide-1 (GLP-1) stimulates glucose-dependent insulin secretion. Dipeptidyl peptidase-4 (DPP-4) inhibitors, which block inactivation of GLP-1, are currently in clinical use for type 2 diabetes mellitus. Recently, GLP-1 has also been reported to have neuroprotective effects in cases of...

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Detalles Bibliográficos
Autores principales: Kim, Soojin, Jeong, Jaewon, Jung, Hye-Seon, Kim, Bokyung, Kim, Ye-Eun, Lim, Da-Sol, Kim, So-Dam, Song, Yun Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597553/
https://www.ncbi.nlm.nih.gov/pubmed/28912645
http://dx.doi.org/10.5607/en.2017.26.4.227