Cargando…

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

The centromere is the chromosomal locus at which the kinetochore is assembled to direct chromosome segregation. The histone H3 variant, centromere protein A (CENP-A), is known to epigenetically mark active centromeres, but the mechanism by which CENP-A propagates at the centromere, replacing histone...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Eun Shik, Cheon, Youngseo, Kang, Keunsoo, Lee, Daeyoup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597579/
https://www.ncbi.nlm.nih.gov/pubmed/28904333
http://dx.doi.org/10.1038/s41467-017-00704-3