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Thiopurine S-Methyltransferase Polymorphisms in Korean Dermatologic Patients

BACKGROUND: Thiopurine S-methyltransferase (TPMT) is an important enzyme in the metabolism of thiopurines including azathioprine (AZA), 6-mercaptopurine, and 6-thioguanine. TPMT genotyping is widely used for screening of AZA-related toxicity during routine clinical practice in Korea. However, the da...

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Detalles Bibliográficos
Autores principales: Lee, Minseok, Seo, Jimyung, Bang, Dongsik, Kim, Do Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597644/
https://www.ncbi.nlm.nih.gov/pubmed/28966507
http://dx.doi.org/10.5021/ad.2017.29.5.529