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Evaluation of the Population Pharmacokinetic Properties of Lidocaine and its Metabolites After Long-Term Multiple Applications of a Lidocaine Plaster in Post-Herpetic Neuralgia Patients

BACKGROUND AND OBJECTIVES: Lidocaine 5% medicated plaster is the first lidocaine containing product for chronic use. As no previous investigations have been conducted to evaluate the population pharmacokinetics of long-term exposure to lidocaine 5% medicated plasters, further insights into the evalu...

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Detalles Bibliográficos
Autores principales: Bursi, Roberta, Piana, Chiara, Grevel, Joachim, Huntjens, Dymphy, Boesl, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597703/
https://www.ncbi.nlm.nih.gov/pubmed/28078530
http://dx.doi.org/10.1007/s13318-017-0400-7