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Bioanalytical development and validation of liquid chromatographic–tandem mass spectrometric methods for the quantification of total and free cefazolin in human plasma and cord blood
OBJECTIVES: Cefazolin is a commonly prescribed β-lactam antibiotic for prophylaxis against skin infections following surgery, including caesarean sections. Assessment of maternal and neonatal exposure is important for correlating drug concentrations to clinical outcomes. Thus, bioanalytical methods...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597705/ https://www.ncbi.nlm.nih.gov/pubmed/28932794 http://dx.doi.org/10.1016/j.plabm.2015.03.003 |