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Are Tumor Cell Lineages Solely Shaped by Mechanical Forces?

This paper investigates cell proliferation dynamics in small tumor cell aggregates using an individual-based model (IBM). The simulation model is designed to study the morphology of the cell population and of the cell lineages as well as the impact of the orientation of the division plane on this mo...

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Detalles Bibliográficos
Autores principales: Leroy-Lerêtre, Mathieu, Dimarco, Giacomo, Cazales, Martine, Boizeau, Marie-Laure, Ducommun, Bernard, Lobjois, Valérie, Degond, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597711/
https://www.ncbi.nlm.nih.gov/pubmed/28852950
http://dx.doi.org/10.1007/s11538-017-0333-y