Fisetin targets phosphatidylinositol-3-kinase and induces apoptosis of human B lymphoma Raji cells

Aberrant regulation of phosphatidylinositol-3-kinases (PI3Ks) is known to be involved in the progression of cancers. PI3K-binding flavonoids such as quercetin and myricetin have been shown to inhibit PI3K activity, but the direct targeting of fisetin to PI3K has not been established. Here, we carrie...

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Detalles Bibliográficos
Autores principales: Lim, Ji Yeon, Lee, Joo Yun, Byun, Byung Jin, Kim, Seong Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598213/
https://www.ncbi.nlm.nih.gov/pubmed/28962438
http://dx.doi.org/10.1016/j.toxrep.2015.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598213/
https://www.ncbi.nlm.nih.gov/pubmed/28962438
http://dx.doi.org/10.1016/j.toxrep.2015.07.004

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