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Hepatoprotective agent tethered isoniazid for the treatment of drug-induced hepatotoxicity: Synthesis, biochemical and histopathological evaluation

The aim of the study was to investigate the protective effect of isoniazid–curcumin conjugate (INH–CRM) in INH-induced hepatic injury by biochemical analysis and histology examination of liver in Wistar rats. The biochemical analysis included determination of the levels of plasma cholesterol, trigly...

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Detalles Bibliográficos
Autores principales: Singh, Charan, Jodave, Laxmikant, Bhatt, Tara Datt, Gill, Manjinder Singh, Suresh, Sarasija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598226/
https://www.ncbi.nlm.nih.gov/pubmed/28962300
http://dx.doi.org/10.1016/j.toxrep.2014.10.001