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Ascorbic acid attenuates antineoplastic drug 5-fluorouracil induced gastrointestinal toxicity in rats by modulating the expression of inflammatory mediators

Damage to the mucous membrane is a serious issue associated with chemotherapy. Gastrointestinal (GI) toxicity is complex and multistep process and unregulated production of reactive oxygen species (ROS) and inflammatory mediators play vital role in the development of GI toxicity. In the present stud...

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Detalles Bibliográficos
Autores principales: Al-Asmari, Abdulrahman Khazim, Khan, Abdul Quaiyoom, Al-Qasim, Amal Mohammad, Al-Yousef, Yara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598240/
https://www.ncbi.nlm.nih.gov/pubmed/28962429
http://dx.doi.org/10.1016/j.toxrep.2015.06.006