Silica nanoparticles induce endoplasmic reticulum stress response, oxidative stress and activate the mitogen-activated protein kinase (MAPK) signaling pathway

Application of silica nanoparticles (SiO(2)-NPs) may result in human exposure. Here we investigate unexplored modes of action by which SiO(2)-NPs with average size of 225 nm act on human hepatoma cells (Huh7). We focused on the endoplasmic (ER) stress response and on mitogen-activated protein kinase...

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Detalles Bibliográficos
Autores principales: Christen, Verena, Camenzind, Magdalena, Fent, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598250/
https://www.ncbi.nlm.nih.gov/pubmed/28962324
http://dx.doi.org/10.1016/j.toxrep.2014.10.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598250/
https://www.ncbi.nlm.nih.gov/pubmed/28962324
http://dx.doi.org/10.1016/j.toxrep.2014.10.023

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